13th BMP conference

Virtual BMP forum


Registration form for the 1st virtual BMP forum is available on the following link:

You have an opportunity to register once for all or only some of the events.


Dear colleagues and friends,


As the International BMP conference in Dubrovnik this coming October had to be postponed due to the Covid19-restrictions, we (An Zwijsen, Slobodan Vukicevic and Petra Knaus) decided to cover the time from September 2020 to summer 2022 with the 1st Virtual BMP Forum, as an Appetizer for the Dubrovnik Meeting October 2022.

We very much hope to get as many of you on board as possible and even reach those interested in BMP research which are new to the community and might not have attended the International BMP conferences before. So please feel free to send this invitation to your colleagues.

We will meet every 3 weeks for 2 talks (each 35 min plus 10 min QA) on a related topic, ideally by 2 speakers from different institutions and even more ideally a young and a more senior scientist. This meeting series aims to complement rather than to duplicate the Dubrovnik speakers list.

Registration to the webinar will be opened by September 1st 2020. All information will be available on the International BMP conference homepage and we will try to update this as frequently as possible.


Meet-the-speakers (After every session, 5:30 pm)



Please already save the following dates:

16:00-17:30 European Time

Summer: GMT + 02:00, Sept-Oct, Apr-June

Winter: GMT + 01:00, Nov-March


Sep 23rd  2020:                   Session 1:   BMP Signalling in Vascular Biology

Oct 14th 2020:                     Session 2:   BMP Signalling and Mechanobiology

Nov 4th 2020:                     Session 3:   BMP Signalling in Cancer

Nov 25th 2020:                   Session 4:   BMP Signalling in Rare Disease

Jan 13th 2021:                     Session 5:   BMP Signalling in Bone and Cartilage Biology

Feb 3rd 2021:                      Session 6:   BMP Signalling in Muscle Biology

Feb 24th 2021:                    Session 7:   Structure of BMP Signalling Components

Mar 17th 2021:                    Session 8:   BMP Co-receptors and Pro-domains

Apr 7th 2021:                      Session 9:   BMP Receptors

Apr 28th 2021:                   Session 10: BMPs and Stem Cells

May 19th 2021:                  Session 11: BMP antagonists

Jun 9th 2021:                     Session 12: BMPs in reproduction

Jun 30th 2021:                   Session 13: Modelling the Pathway

Jul 28st 2021:                    Session 14: BMPs in neurodevelopment

Sep 15th 2021:                    Session 15: BMP pathway in clinical settings

Oct 6th 2021:                      Session 16: BMP signalling and Stem Cells 2

Oct 27th 2021:                    Session 17: BMP and Cancer 2

Nov 17th 2021:                    Session 18: BMP and iron regulation

Dec 8th 2021:                     Session 19: BMP and disease

Jan 19th 2022:                    Session 20: BMP signaling and Vascular Biology 2

Feb 9th 2022:                    Session 21: New Voices in BMP Research

Mar 2nd 2022:                    Session 22: BMP signalling in heart regeneration

Apr 27th 2022:                    Session 23: SMADs and genomic accessibility

May 25th 2022:                    Session 24: Craniofacial development, how our faces are shaped by BMP


Confirmed speakers, 1st Virtual BMP-forum:


Wei LI, Cambridge/UK

Franck LEBRIN, Leiden/Netherlands

Chris HIEPEN, Berlin/Germany

Boris HINZ, Toronto/Canada

Toril HOLIEN, Trondheim/Norway

Antonio VIDAL-PUIG, Cambridge/UK

John LEES-SHEPARD, Tarrytown/US

Rozenn QUARCK, Leuven/Belgium

Maurizio PACIFICI, Philadelphia/USA

Reinhard WINDHAGER, Vienna/Austria

Sigmar STRICKER, Berlin/Germany

Helge AMTHOR, Montigny-le-Bretonneux/France

Erich GOEBEL, Cincinnati/USA

Maria MACIAS, Barcelona/Spain

Christian SIEBOLD, Oxford/UK

Gerhard SENGLE, Cologne/Germany

Senem AYKUL, Tarrytown/USA

Corinne ALBIGES-RIZO, Grenoble/France

Valeria ORLOVA, Leiden/NL

Jennifer ESSER, Freiburg/Germany

Mihaela PERIC, Zagreb/Croatia

Alex LÖWER, Darmstadt/Germany

Tim HERPELINCK, Leuwen/Belgium

Hyeyoon LEE, Heidelberg/Germany


Berna SOZEN, Connecticut, USA

Michael ELOWITZ, Pasadena,CA/USA

Soheila KARIMI, Winnipeg/Canada

Christian SCHACHTRUP, Freiburg/Germany

Nick MORREL, Cambridge/UK

Nicole INFARINATO, Rockfeller/USA

Yuan LIU, Beijing/ China

Qiaoran XI, Beijing/ China

Tetsuro WATABE, Tokyo/Japan

Richard COFFEY, Boston/USA

Xia XIAO, Boston/USA

Mark ORMISTON, Ontario/Canada

Christophe GUIGNABERT, Paris, France

Lei WANG, Bad Neuheim/Germany

William SESSA, New Haven/USA

Alexander BANKS, Cambridge/USA

Shailesh AGARWAL, Cambridge/USA

Anke SMITS, Leiden/the Netherlands

Serena ZACCHIGNA, Trieste/Italy

Jerome JATZLAU, Berlin/Germany

Jose Carlos REYES, Sevilla/Spain

Jingwen YANG, Wuhan/China

Wei HSU, Harvard/USA



16:00-17:30 European Time

Summer: GMT + 02:00, Sept-Oct, Apr-June

Winter: GMT + 01:00, Nov-March


Sep 23rd 2020: BMP Signalling in Vascular Biology

Chair: Gonzalo Sanchez-Duffhues, Leiden/Netherlands

Wei LI, Cambridge/UK

“Molecular regulation of BMP9 and 10 signalling in vascular endothelial cells“

Franck LEBRIN, Leiden/Netherlands

“From mechanisms to therapy in Hereditary Hemorrhagic Telangiectasia”


Oct 14th 2020: BMP Signalling and Mechanobiology

Chair: Ada Cavalcanti-Adam, Heidelberg/Germany

Chris HIEPEN, Berlin/Germany

“BMPR2 and endothelial cell mechanics, an old player in a new light”

Boris HINZ, Toronto/Canada

“How transforming growth factor mechanics affect fibroblast morphogenesis”


Nov 4th 2020: BMP Signalling in Cancer

Chair: Aris Moustakas, Uppsala/Sweden

Toril HOLIEN, Trondheim/Norway

“Regulating the tumor suppressing activity of ALK2 in multiple myeloma”

Antonio Vidal-Puig, Cambridge/UK

“Metabolic Role of BMP8b”


Nov 25th 2020: BMP Signalling in Rare Disease

Chair: Fumiko Itoh, Tokyo/Japan

John LEES-SHEPARD, Tarrytown/USA

“Activin A is necessary for heterotopic ossification in adult ACVR1[R258G] and ACVR1[R206H] FOP-mice, but each model exhibits a distinct developmental phenotype”

Rozenn QUARCK, Leuven/Belgium

“Balancing BMPRII and TGFβ signaling pathways in pulmonary arterial hypertension: potential treatment perspectives”


Jan 13th 2021: BMP Signalling in Bone and Cartilage Biology

Chair: Johanna Bolander, Boston, USA/ Leuven, Belgium

Maurizio PACIFICI, Philadelphia/USA

“Roles and mechanisms of BMP and Activin action in heterotopic ossification”

Reinhard WINDHAGER, Vienna/Austria

“Recombinant human BMP6 applied within Autologous Blood Coagulum accelerates bone healing: Randomized controlled trial in High Tibial Osteotomy patients”


Feb 3rd 2021: BMP Signalling in Muscle Biology

Chair: Hans Georg Simon, Chicago/USA

Sigmar STRICKER, Berlin/Germany

“An unbalanced BMP-biomechanical niche reveals the plasticity of the mammalian myogenic lineage”

Helge AMTHOR, Montigny-le-Bretonneux/France

“BMP signaling patterns limb muscle”


Feb 24th 2021: Structure of BMP Signalling Components

Chair: Alex Bullock, Oxford/UK

Erich GOEBEL, Cincinnati/USA

“Detailing Activin Receptor Specificity Mechanisms”

Maria MACIAS, Barcelona/Spain

“Structural Insights into Smad Function”


Mar 17th 2021: BMP Co-receptors and Pro-domains

Chair: Jerome Jatzlau, Berlin/Germany

Christian SIEBOLD, Oxford/UK

“Molecular Mechanisms of Repulsive Guidance Molecule(RGM) Signalling”

Gerhard SENGLE, Cologne/Germany

“A new matrix metalloproteinase mediated prodomain cleavage mechanism to activate BMP growth factors from the extracellular matrix”


Apr 7th 2021: BMP Receptors

Chair: Paul Upton, Cambridge/UK

Senem AYKUL, Tarrytown/US

“Dimerization of FOP-mutant ACVR1 induces P-Smad1/5/8
signalling in a Type II receptor dependent manner”

Corinne Albiges-Rizo, Grenoble/France

“Focal Adhesions are sites of segregation for BMP receptors”


Apr 28th 2021: BMPs and Stem Cells

Chair: Ruben Dries, Boston/USA

Valeria ORLOVA, Leiden/Netherlands

“3D vessel-on-chip to model vascular disease and beyond”

Tim HERPELINCK, Leuven/Belgium

“A single-cell atlas of skeletal tissues to study inter- and intracellular signalling: a BMP case study”


May 19th 2021: BMP antagonists

Chair: Przemko TYLZANOWSKI, Leuven/Belgium

Jennifer ESSER, Freiburg/Germany

“The BMP modulator BMPER: effects on angiogenesis, angiopathy and angioregeneration”

Hyeyoon LEE, Heidelberg/Germany

“R-spondins are new BMP receptor antagonists in early embryonic development”


Jun 9th 2021: BMPs in reproduction

Chair: Susana Chuva de sousa lopes Leiden/The Netherlands

Diana MONSIVAIS, Houston/USA

“An endometrial BMP signalling axis controls receptivity and embryo implantation”

Berna SOZEN, Connecticut/USA

„The role of BMP signalling in early mammalian embryo development”


Jun 30th 2021: Modelling the Pathway

Chair: Caroline Hill, London/UK

Alexander LOEWER, Darmstadt/Germany

“Dynamics and variability of SMAD signalling in single cells”

Michael ELOWITZ, Pasadena/CA/USA

“The context-dependent combinatorial logic of BMP signalling”


Jul 28th 2021: BMPs in neurodevelopment

Chair: Danny HUYLEBROECK, Rotterdam (NL)/Leuven (BE)

Soheila KARIMI, Winnipeg/Canada

“Role and Mechanisms of BMP4 in spinal cord injury”

Christian SCHACHTRUP, Freiburg/Germany

“Fibrinogen–induced BMP signaling modifying stem cell behavior in CNS disease”


Sep 15th 2021: BMP pathway in clinical settings

Chair: Slobodan Vukicevic, Zagreb/Croatia

Mihaela PERIC, Zagreb/Croatia

“Preclinical development of BMP6 based bone regeneration drug/device“

Nick MORELL, Cambridge/UK

“The potential therapeutic use of BMP ligands for vascular diseases”


Oct 6th 2021: BMP signaling and Stem Cells II

Chair: Calle Heldin, Uppsala/Sweden


“Elucidating the role of BMP signalling in melanocyte stem cell activation and differentiation in the hair follicle niche”

Yuan LIU, Beijing/China

“A role of BMP pathway in intestinal homeostasis maintenance and colitis formation”


Oct 27th 2021: BMPs and Cancer II

Chair: Kohei Miyazono, Tokyo/Japan

Qiaoran XI, Beijing, China

“BMPs exert tumor suppressive effects by forcing a subtype of diffuse intrinsic pontine glioma (DIPG) to exit from stemness state through epigenetic regulation of CXXC5”

Tetsuro WATABE, Tokyo, Japan

“Roles of TGF-βfamily signals during progression of oral cancer”


Nov 17th 2021: BMPs and Iron regulation

Chair: Jodie Babitt, Boston/USA

Richard COFFEY Los Angeles, USA

“Erythroferrone: a novel BMP antagonist and erythroid regulator of iron metabolism”C5”“

Xia XIAO, Boston, USA

“BMP ligands in hepcidin and iron homeostasis regulation”


Dec 8th 2021: The Paradox of BMP9/BMP10 Signaling in Vascular Homeostasis, PAH and HHT

Chair: Paul B. Yu, Boston/USA

Mark ORMISTON, Ontario, Canada

“Examining the transcriptomic basis for prolonged BMP9 signaling kinetics and hyperproliferation in the BMPR2-deficient pulmonary endothelium”

Christophe GUIGNABERT, Paris, France

“BMP-9 and BMP-10: Roles in Cardiopulmonary Vascular Homeostasis and Remodeling”


Jan 19th 2022: BMP signaling and Vascular Biology 2

Chair: Sabine Bailly, Grenoble/France

Lei WANG, Bad Neuheim/Germany

“The role of BMP9 and BMP10 for vascular smooth muscle cells”

William SESSA, New Haven/USA

“Non-canonical role for ALK1 in atherosclerosis”


Feb 9th 2022: New Voices in BMP Research

Chair: Vicki ROSEN, Cambridge/USA

Alexander BANKS, Cambridge/USA

“Gdf3 regulates metabolism by simultaneously antagonizing BMP signaling and agonizing TGF beta signalling”

Shailesh AGARWAL, Cambridge/USA

“Leveraging BMP signaling for cellular therapy”


Mar 2nd 2022: BMP signalling in heart regeneration

Chair: Marie-José GOUMANS, LUMC/the Netherlands

Anke SMITS, Leiden/the Netherlands

“The epicardium in cardiac regeneration, a
potential role for Activin/Alk4 in epicardial EMT”

Serena ZACCHIGNA, Trieste/Italy

“Anti-BMP1.3 antibody: a new biologic for cardiac disease”


Apr 27th 2022: SMADs and genomic accessibility

Chair: Marie MACIAS, Barcelona/Spain

Jerome JATZLAU, Berlin/Germany

“BMP9 and Fluid Shear Stress regulate endothelial chromatin accessibility and expression of SMAD low affinity target genes”

Jose Carlos REYES, Sevilla/Spain

“Regulation of enhancers and coexpression domains by TGFβ”


May 25th 2022: Craniofacial development, how our faces are shaped by BMP

Chair: Yuji MISHINA, Michigan/USA

Jingwen YANG, Wuhan/China

“A BMP-controlled metabolic-epigenetic signaling cascade directs midfacial morphogenesis”

Wei HSU, Harvard/USA

“BMPR1A in skeletal stem cell-mediated craniofacial development, disease, and regeneration”